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Neurochemistry Research Group

Division of Neurosurgery

Studying at Cambridge

 

2010 - 2015

Published in 2015:

'Recombinant human interleukin-1 receptor antagonist promotes M1 microglia biased cytokines and chemokines following human traumatic brain injury'
by Adel Helmy, Mathew R. Guilfoyle, Keri L.H. Carpenter, John D. Pickard, David K. Menon, and Peter J. Hutchinson.
Journal of Cerebral Blood Flow and Metabolism, 2015. Full article available here.

'Glycolysis and the significance of lactate in traumatic brain injury'
by Keri L.H. Carpenter, Ibrahim Jalloh, and Peter J. Hutchinson.
Frontiers in Neuroenergetics, 2015. Full article available here.

'Systemic, local, and imaging biomarkers of brain injury: more needed, and better use of those already established?'
by Keri L.H. Carpenter, Marek Czosnyka, Ibrahim Jalloh, Virginia F.J. Newcombe, Adel Helmy, Richard J. Shannon, Karol P. Budohoski, Angelos G. Kolias, Peter J. Kirkpatrick, Thomas Adrian Carpenter, David K. Menon, and Peter J. Hutchinson.
Frontiers in Neurology, 2015. Full article available here.

'Matrix Metalloproteinase Expression in Contusional Traumatic Brain Injury: A Paired Microdialysis Study'
by Mathew R. Guilfoyle, Keri L.H. Carpenter, Adel Helmy, John D. Pickard, David K. Menon, and Peter J.A. Hutchinson.
Journal of Neurotrauma, 2015. Full article available here.

'Consensus statement from the 2014 International Microdialysis Forum 8'
by Peter J. Hutchinson, Ibrahim Jalloh, Adel Helmy, Keri L. Carpenter, Elham Rostami, Bo-Michael Bellander, Martyn G. Boutelle, Jeff W. Chen, Jan Claassen, Claire Dahyot-Fizelier, Per Enblad, Clare N. Gallagher, Raimund Helbok, Lars Hillered, Peter D. Le Roux, Sandra Magnoni, Halinder S. Mangat, David K. Menon, Carl-Henrik Nordström, Kristine H. O'Phelan, Mauro Oddo, Jon Perez Barcena, Claudia Robertson, Elisabeth Ronne-Engström, Juan Sahuquillo, Martin Smith, Nino Stocchetti, Antonio Belli, T. Adrian Carpenter, Jonathan P. Coles, Marek Czosnyka, Nil Dizdar, J. Clay Goodman, Arun K. Gupta, Troels H. Nielsen, Niklas Marklund, Ambroise Montcriol, Mark T. O'Connell, Maria A. Poca,  Asita Sarrafzadeh, Richard J. Shannon, Jane Skjøth-Rasmussen, Peter Smielewski, John F. Stover, Ivan Timofeev, Paul Vespa, Elizabeth Zavala, and Urban Ungerstedt.
Intensive Care Medicine, 2015. Full article available here.

Published in 2014:

'Glucose metabolism following human traumatic brain injury: methods of assessment and pathophysiological findings'
by Ibrahim Jalloh, Keri L.H. Carpenter, Adel Helmy, T. Adrian Carpenter, David K. Menon, and Peter J. Hutchinson.
Metabolic Brain Disease, 2014. Full article available here.

'Glycolysis and pentose phosphate pathway after human traumatic brain injury: microdialysis studies using 1,2-13C2 glucose'
by Ibrahim Jalloh, Keri L.H. Carpenter, Peter Grice, Duncan J. Howe, Andrew Mason, Claire N. Gallagher, Adel Helmy, Michael P. Murphy, David K. Menon, T. Adrian Carpenter, John D. Pickard, and Peter J. Hutchinson.
Journal of Cerebral Blood Flow & Metabolism, 2014. Full article available here.

'Recombinant Human Interleukin-1 Receptor Antagonist in Severe Traumatic Brain Injury: A Phase II Randomized Control Trial'
by Adel Helmy, Mathew R. Guilfoyle, Keri L.H. Carpenter, John D. Pickard, David K. Menon, and Peter J. Hutchinson.
Journal of Cerebral Blood Flow & Metabolism, 2014. More details available here.

'Response to Letter - Lactate uptake against a concentration gradient: misinterpretation of analytical imprecision'
by Ibrahim Jalloh, Adel Helmy, Richard J. Shannon, Clare N. Gallagher, David K. Menon, Keri L.H. Carpenter, and Peter J. Hutchinson.
Journal of Neurotrauma, 2014. Full article available here.

'Monitoring vigabatrin in head injury patients by cerebral microdialysis: obtaining pharmacokinetic measurements in a neurocritical care setting'
by Richard J. Shannon, Ivan Timofeev, Jürgens Nortje, Peter J. Hutchinson, and Keri L. H. Carpenter.
British Journal of Clinical Pharmacology, 2014. More details available here.

'13C-labelled microdialysis studies of cerebral metabolism in TBI patients'
by Keri L.H. Carpenter, Ibrahim Jalloh, Clare N. Gallagher, Peter Grice, Duncan J. Howe, Andrew Mason, Ivan Timofeev, Adel Helmy, Michael P. Murphy, David K. Menon, Peter J. Kirkpatrick, T. Adrian Carpenter, Garnette R. Sutherland, John D. Pickard, and Peter J. Hutchinson.
European Journal of Pharmaceutical Sciences, 2014. More details available here.

 

Published in 2013:

'Lactate uptake by the injured human brain: Evidence from an arteriovenous gradient and cerebral microdialysis study'
by Ibrahim Jalloh , Adel Helmy, Richard J. Shannon, Clare N. Gallagher, David K. Menon, Keri L.H. Carpenter, and Peter J. Hutchinson.
Journal of Neurotrauma, 2013. More details available here.

'Cerebral microdialysis in clinical studies of drugs: pharmacokinetic applications'
by Richard J. Shannon, Keri L. H. Carpenter, Mathew R. Guilfoyle, Adel Helmy, and Peter J. Hutchinson.
Journal of Pharmacokinetics and Pharmacodynamics, 2013. More details available here.

Published in 2012:

'Principal component analysis of the cytokine and chemokine response to human traumatic brain injury'
by Adel Helmy, Chrystalina A. Antoniades, Mathew R. Guilfoyle, Keri L. H. Carpenter, and Peter J. Hutchinson.
PLOS one, 2012. More details available here.

Published in 2011:

'The cytokine response to human traumatic brain injury: temporal profiles and evidence for cerebral parenchymal production'
by Adel Helmy, Keri L H Carpenter, David K Menon, John D Pickard, and Peter J A Hutchinson.
Journal of Cerebral Blood Flow and Metabolism, 2011. More details available here.

'Cytokines and innate inflammation in the pathogenesis of human traumatic brain injury'
by Adel Helmy, Maria-Grazia De Simoni, Mathew R. Guilfoyle, Keri L.H. Carpenter, and Peter J. Hutchinson.
Progress in Neurobiology, 2011. More details available here.

'Cerebral extracellular chemistry and outcome following traumatic brain injury: a microdialysis study of 223 patients'
by Ivan Timofeev, Keri L. H. Carpenter, Jürgens Nortje, Pippa G. Al-Rawi, Mark T. O'Connell, Marek Czosnyka, Peter Smielewski, John D. Pickard, David K. Menon, Peter J. Kirkpatrick, Arun K. Gupta, and Peter J. Hutchinson.
Brain, 2011. More details available here.

'Interaction between brain chemistry and physiology after traumatic brain injury: impact of autoregulation and microdialysis catheter location'
by Ivan Timofeev, Marek Czosnyka, Keri L.H. Carpenter, Jürgens Nortje, Peter J. Kirkpatrick, Pippa G. Al-Rawi, David K. Menon, John D. Pickard, Arun K. Gupta, and Peter J. Hutchinson.
Journal of Neurotrauma, 2011. More details available here.

Published in 2010:


'In vivo assessment of high-grade glioma biochemistry using microdialysis: a study of energy-related molecules, growth factors and cytokines'
by Hani J. Marcus, Keri L. H. Carpenter, Stephen J. Price, and Peter J. Hutchinson
Journal of Neuro-Oncology, 2010. More details available here.